Role of the Rep helicase gene in homologous recombination in Neisseria gonorrhoeae.

نویسندگان

  • Kimberly A Kline
  • H Steven Seifert
چکیده

In Escherichia coli, the Rep helicase has been implicated in replication fork progression, replication restart, homologous recombination, and DNA repair. We show that a Neisseria gonorrhoeae rep mutant is deficient in the homologous-recombination-mediated processes of DNA transformation and pilus-based colony variation but not in DNA repair.

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عنوان ژورنال:
  • Journal of bacteriology

دوره 187 8  شماره 

صفحات  -

تاریخ انتشار 2005